Lupus is a chronic, autoimmune disease, which causes inflammation of various parts of the body, especially the skin, joints, blood or kidneys. The immune system normally protects the body against viruses, bacteria and other foreign invaders. Lupus affects the immune system so that it is unable to distinguish the body’s own cells and tissues from foreign matter. The immune system may attack different parts of the body causing inflammation, injury and/or pain.

Lucy Vodden, who provided the inspiration for the Beatles' classic song "Lucy in the Sky with Diamonds," has died after a long battle with lupus. She was 46.